Researchers from Liverpool School of Tropical Medicine have helped uncover how ticks mount a defense against a deadly virus ...

In order to deliver its genetic cargo, SRP-9003 uses a viral vector, a virus that’s been engineered so it will deliver a therapeutic gene into cells. The vector used in SRP-9003, called rAAVrh74, is ...

Make sure these programs have been installed before using VirStrain. (However, if you use bioconda/pip to install VirStrain, ignore this.) Then, you can download the reference database of 3 RNA ...

RNA viruses (i.e. alphaviruses) employ sophisticated strategies to avoid host defenses and develop persistent infection. ... (DI) particles, a defective viral genome that is capable of replication and ...

Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today announced that the rAAVrh74 viral vector used in the investigational gene therapy SRP-9003 ...

Introduction: Adeno-associated virus (AAV) vectors are promising tools for cancer gene therapy, yet their clinical application in head and neck squamous cell carcinoma (HNSCC) is hindered by ...

In a new study, using three-letter “triplet” RNA, scientists induced RNA replication by preventing the RNA double helix from zipping together. Where did we all come from? It’s a question ...

The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlighted a critical need to discover more effective antivirals. While therapeutics for SARS-CoV-2 exist, ...

RNA strands zip up into a double helix that blocks their replication. Like Velcro, these are hard to pull apart and quick to stick back together, leaving no time to copy them. In a study described ...

RNA strands zip up into a double helix that blocks their replication. Like velcro, these are hard to pull apart and quick to stick back together, leaving no time to copy them. In a study described ...

RNA strands zip up into a double helix that blocks their replication. Like velcro, these are hard to pull apart and quick to stick back together, leaving no time to copy them.