Natural human monoclonal antibodies obtained from sentinel lymph nodes of cancer patients identify cell surface vimentin. One of these vimentin-reactive antibodies, pritumumab, has been used to treat ...

Vimentin, a type III intermediate filament (IF) protein, is primarily expressed in mesenchymal cells, which give rise to connective tissue, blood vessels, and lymphatic tissue. Despite extensive ...

研究人员通过分析 TCGA 数据库，发现 miR-101-3p 在肝癌组织中的表达低于正常组织，且其低表达与肝癌患者的不良预后相关。在临床样本和细胞系中也证实了这一点，像 QGY7701 和 HepG2 这些肝癌细胞系中 miR-101-3p 的表达明显低于正常细胞。

The journal Advanced Materials recently published a study introducing a new method for monitoring molecular processes deep ...

在这样的背景下，锦州医科大学附属第一医院等机构的研究人员开展了一项关于 3,3′?二吲哚甲烷（DIM）治疗 NSCLC 的研究。该研究成果发表在《Discover Oncology》上，为 NSCLC 的治疗带来了新的曙光。

Methods HBECs from non-smokers (n=5), smokers (n=12) and patients with COPD (n=15) were collected to measure the mesenchymal markers α-smooth muscle actin, vimentin and collagen type I and the ...

Additionally, mesenchymal markers like Vimentin and α-SMA were also diminished, while epithelial markers such as E-cadherin, Occludin, and ZO-1 were elevated, suggesting a disrupted EMT process.

Hypospadias is a widespread congenital disorder, characterized by an abnormal placement of the urethral opening, impacting as ...

Cellular unjamming is the collective fluidization of cell motion and has been linked to many biological processes, including development, wound repair, and tumor growth. In tumor growth, the ...

本文研究结果表明，通过RNA干扰技术来靶向作用波形蛋白或XIST或能作为一种很有前景的乳腺癌新型疗法策略。 波形蛋白(vimentin)是一种III型中间丝状 ...

A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common ...