Abstract: We aimed to characterize the impact of anti-gravity locomotion training on the structure and function of the corticospinal tract (CST) in cerebral palsy (CP). Fourteen CP children ...

Abstract: This paper reports on a corticospinal interface IC as a core building block for next-generation integrated neural interfaces targeted at functional recovery from spinal cord injury (SCI).

To date, TMS studies have established motor cortical and corticospinal dysfunction in ALS, with cortical hyperexcitability being an early feature in sporadic forms of ALS and preceding the clinical ...

The most well-studied subtype of subcerebral projection neuron is corticospinal motor neurons (CSMNs). During the last several years the identification of a large number of subcerebral- and CSMN ...

We here utilize an online resource containing high-resolution images with tract-tracing data (Zakiewicz et al ... In two cases injected in S1 whisker representations, we observed a few labeled fibers ...

Department of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom Motor neuron disease can be viewed as an umbrella term ...

In hTDP-43ΔNLS mice, extensive gliosis developed in regions affected by neurodegeneration (i.e., the neocortex and dentate gyrus). Gliosis also was noted at all levels of the corticospinal tract, as ...

This observational study from the UK Biobank provides an important investigation into the associations between menopausal hormone therapy and brain health in a large, population-based cohort of ...

Urinary tract infections (UTIs) are a common burden in patients with diabetes mellitus. Cystitis, ascending infections leading to pyelonephritis, emphysematous complications and renal and ...

Stroke is increasingly understood as a network disorder with symptoms often arising from disruption of white matter connectivity. Previous connectome-based lesion-symptom mapping studies revealed that ...