Valproic acid (VPA), formally 2-propylpentanoic acid, is a low–molecular weight branched-chain fatty acid ... even though an inspection of its structure shows that that cannot be true. VPA is widely ...

For instance, the medication changes the levels of certain chemical ... structure and function is similar to that of the full-size organ. The researchers exposed the organoids to valproic acid ...

Sold under brand names that include Depakene, Depakote and Stavzor, valproic acid is used ... methods to solve chemical problems ― to screen the chemical structures of more than 1,700 food ...

In a prospective trial, patients treated with oral valproic acid for autosomal dominant retinitis ... Regeneron, 4D Molecular Therapeutics and Second Sight Medical Products outside the submitted ...

Although the risk for spina bifida appears to be increased with the use of valproic acid in the first trimester of pregnancy, evidence to date is limited regarding the risk for other congenital ...

The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but data on the risks of other congenital malformations are limited. We first ...

Valproic acid has been shown to exert neuroprotective ... China; 2 Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Cytology and Genetics, Northeast Normal University ...

Valproic acid dissociates to form valproate ... types of seizures that are characterized by unique molecular events. Gamma-aminobutyric acid (GABA) is an important neurotransmitter that is widely ...

Valproic acid is an anticonvulsant medication that works by changing the concentration of certain neurotransmitters in the brain. It is most commonly used in the prevention of epileptic seizures ...