The antiepileptic drug valproic acid (VPA) has been shown to influence the neural differentiation and neurite outgrowth of neural stem cells. Sympathoadrenal progenitor cells share properties with ...

Valproic acid (VPA), formally 2-propylpentanoic acid, is a low–molecular weight branched-chain fatty acid ... even though an inspection of its structure shows that that cannot be true. VPA is widely ...

Valproic acid dissociates to form valproate ... types of seizures that are characterized by unique molecular events. Gamma-aminobutyric acid (GABA) is an important neurotransmitter that is widely ...

For instance, the medication changes the levels of certain chemical ... structure and function is similar to that of the full-size organ. The researchers exposed the organoids to valproic acid ...

Valproic acid has been shown to exert neuroprotective ... China; 2 Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Cytology and Genetics, Northeast Normal University ...

Researchers have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures. University of California, Irvine ...

The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but data on the risks of other congenital malformations are limited. We first ...

Valproic Acid: A Happy Accident, Again? A recent study suggested that patients with glioblastoma treated with radiation and temozolomide lived a few months longer if they were taking valproic acid ...

Although the risk for spina bifida appears to be increased with the use of valproic acid in the first trimester of pregnancy, evidence to date is limited regarding the risk for other congenital ...

Please can you give a brief introduction to valproic ... valproic acid. Our manuscript describing the studies that we performed have been reported in the January 2014 issue of Molecular Pharmacology.

In a prospective trial, patients treated with oral valproic acid for autosomal dominant retinitis ... Ionis Pharmaceuticals, Regeneron, 4D Molecular Therapeutics and Second Sight Medical Products ...