Onctura has dosed the first subject in the Phase II OCULE-01 trial of oral roginolisib in individuals with metastatic uveal ...

The summer of 2023 saw the approval of a new treatment option for certain patients with uveal melanoma, a form of cancer that begins in the eye and remains a challenge to treat. Richard Staines ...

As many as half of people diagnosed with uveal melanoma (ocular melanoma) go on to have what’s called metastatic disease. Most often, the cancer metastasizes (spreads) beyond the eye to the ...

In the Phase I DIONE-01 study roginolisib demonstrated an excellent safety profile and a doubling of overall survival in metastatic uveal melanoma patients compared to historical controls.

Fitzpatrick skin type influences both characteristics and outcomes associated with uveal melanoma and conjunctival melanoma.

Patient-derived organoids can be established from uveal melanoma tumors. Credit: Investigative Ophthalmology & Visual Science (2024). DOI: 10.1167/iovs.65.13.60 ...

The updated NCCN Guidelines now include HEPZATO KIT as a Category 2A treatment option for patients with hepatic-dominant uveal melanoma. Previously, the guidelines limited its use to patients with ...