To determine whether virus-induced accelerated graft rejection was a result of antigen-specific immunity ... in which skin from mice expressing a defined tumor CTL epitope as a transgene was ...

In the field of cancer immunotherapy, unconventional T cells (UCTs) and Chimeric Antigen Receptor (CAR) T cells have emerged as promising areas of research ...

In cancer immunotherapy, robust and efficient activation of cytotoxic CD8+ T cell immune responses is a promising, but challenging task. Dendritic cells (DCs) are well-known professional antigen ...

Minerva Biotechnologies - Overcoming the Solid Tumor Barrier: MUC1*-Targeted CAR T bearing 1XX mutations overcomes exhaustion and enables killing of low antigen expressing cancer cells Business Wire ...

The detection of autoantibodies in cancer patients has been shown to constitute an excellent tool for early diagnosis. Because breast cancer still lacks early diagnostic markers, we investigated novel ...

Background: CA 15.3 is a conventional TM commonly elevated in HR (+) /HER2 (-) ABC at diagnosis and is associated with a high burden of disease and shorter OS during follow-up for response to ...

Background: Tumor lysis syndrome (TLS) is a known complication of hematologic malignancy treatments, often leading to fatal arrhythmias, acute kidney injury, and seizures. Chimeric Antigen Receptor ...

We evaluated the incidence of de novo donor-specific anti-human leukocyte antigens antibodies (DSA) and histology on protocol biopsies at 12 months, and the incidence of acute rejection ...