[1] In their report, the authors develop weighted criteria to prioritize tumor vaccine antigens with the goal of identifying rational criteria to move individual antigens forward in development ...

(Top right) Antigen escape: tumor cells can downregulate or lose the expression of the targeted antigen ... Universal CAR-T cells within this group are engineered to avoid immune rejection and GvHD, ...

Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system ...

A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells ...

Mazed appealed from the rejection of claims 85 and 87 of his ... an origami nanostructure for binding a synthetic peptide tumor antigen as taught by [the prior art] with a reasonable expectation ...

1Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada.

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, Nanjing 210093, China Department of Andrology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical ...