While some mutations in the BRCA2 gene clearly indicate risks for breast and prostate cancer, thousands of less-common ...

A new study reveals a mutation mechanism in osteosarcoma, promising advances in treatment and prognosis for this challenging ...

A research team has identified a crucial link between a gene mutation and immune system signaling in canine hemangiosarcoma, an aggressive cancer common in dogs. The discovery could lead to better ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells ...

The field of cancer research has been significantly focused on understanding the complex interplay between tumor mutations, immune evasion, and resistance to targeted therapies. Tumors are known to ...

Researchers have identified many genes, known as oncogenes, that initiate and drive cancer when mutated. Although scientists have long speculated that mutations protecting against cancer also ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Some DNA damage evades repair for years, causing repeated mutations during cell division, increasing cancer risk, especially ...

Scientists have characterized the role of thousands of mutations in the BRCA2 cancer gene, findings that may help reassure ...

The mutation is found in four out of 10 people with Ashkenazi Jewish ancestry. Out of the 11,000 people tested during the new ...

Diagnosis. Lynch syndrome with a heterozygous germline mutation in MSH2. Management. Debulking of the cerebral tumor, craniospinal axis radiotherapy, and genetic counseling of family. A 30-year ...