Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

Johns Hopkins University School of Medicine, Baltimore, MD.

The dual-targeting approach helps to prevent relapses by addressing the variability among cancer cells in antigen expression. Natural killer (NK) cell function is suppressed by transforming growth ...

1Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee. Search for other works by this author on: 2Department of Computational Biology, St. Jude Children’s Research ...

Department of Biomedical Engineering College of Engineering, Shantou University, Shantou 515063, China ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Bispecific antibodies (bsAbs) exert their function through diverse strategies including T-cell engagement for ... For example, T-cell engagers (TCEs) are bsAbs designed to simultaneously bind CD3 on T ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...