Such translocation mutations can cause disorders of growth, development, and function of the body's cells and systems. Human cell nuclei have 23 pairs of chromosomes. Twenty-two of them are paired ...

In a Robertsonian translocation, acrocentric chromosomes fuse together. This fusing joins two “long arms” of DNA into one. To make studying genes and their mutations easier, ...

When a broken chromosome attaches to another, or when chromosomes use a similar process to exchange genetic material, you've got a translocation – genes end up fused to other genes, ...

Many translocations have been catalogued 9,10 and are listed in databases such as the Database of Chromosome Rearrangements in Disease (dbCRID) and the Catalogue of Somatic Mutations in Cancer ...

This timeframe represents the period between the translocation event (856,000 to 1.3 million years ago) and the most recent common ancestor of all modern human Y chromosomes, dating to around ...

All the translocations that have been found in association with mongolism have involved the acrocentric chromosomes, which have always included at least 1 chromosome in Group 21–22 (by common ...

When a broken chromosome attaches to another, or when chromosomes use a similar process to exchange genetic material, you've got a translocation – genes end up fused to other genes, encoding a ...

Whether spontaneous or induced, mutations generally are a result of large-scale deletions, inversions or translocations of chromosomes, or from point mutations (a type of mutation that causes a single ...

A NEW familial syndrome associated with a translocation between a chromosome No. 3 and a member of the B group (No. 4–5) is described in this report. Among the many family members, 6 infants ...

A recent review shows the role of chromosomal translocations in causing a range of cancers. Emerging, personalized therapies target these translocations. A broken chromosome is like an unmoored ...