Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Intrinsic glycolytic metabolism shapes PD-L1 + macrophages with antitumourigenic properties in HCC. PKM2/HIF-1α axis, elicited by hepatoma cell-derived fibronectin 1, triggers pluripotent polarisation ...