To support physicians in treating cancer patients, oncology laboratories can benefit from adopting end-to-end automation of flow cytometry workflows. Rapid advances in automation are improving ...

These cells branch from conventional MHC-restricted T cells at the CD4 + CD8 + (double positive) stage of development in the thymus. Although the NKT-cell TCRα is invariant, a more diverse ...

The development of MHC class II-restricted thymocytes that lack or express a mutant form of ThPOK is diverted to the CD8 lineage, indicating that ThPOK functions in CD4- or CD8- lineage determination.