Oxime/Methoxime is under clinical development by Bodor Laboratories and currently in Phase II for Unspecified Ophthalmological Disorders. According to GlobalData, Phase II drugs for Unspecified ...

The bacterial cells were grown in LB broth and incubated in the absence or presence of 0.5xMIC of thiophene derivatives for 3 h. The pellet was harvested by ultracentrifugation at 4600g for 15 min.

Abstract: As a non-corrosive inactive sulfur, thiophene is one of the most common sulfides in mineral oil, which are retained in oil and used for improving the oxidation stability of the oil. However, ...

Department of Chemical Engineering and Waterloo Institute for Nanotechnology (WIN), University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada ...

Figure 1. (A–C) Chemical molecular structures of studied thiophene derivatives (the number indicates atom-numbering). In the present work, three earlier mentioned ...

Mutations of conserved residues around this pocket affect activity of the thiophene inhibitors, consistent with allosteric inhibition of DNA gyrase. This druggable pocket provides potentially ...

We report the synthesis and characterization of covalent organic frameworks (COFs) incorporating thiophene-based building blocks. We show that these are amenable to reticular synthesis, and that bent ...