Thiol groups of cysteinyl residues are highly sensitive to oxidation which might critically perturb cellular homeostasis. Members of the thioredoxin superfamily are key proteins involved in the ...

Previously, the current study’s researchers revealed that mucin disulfide crosslinks could be targeted using drugs that contain functional thiol groups, which led to speculation that thiol drugs ...

It has been reported that disulfide units are able to mediate cytosolic uptake of DNA and RNA molecules by disulfide exchange reactions with thiol groups on the cell membrane protein. Therefore, we ...

There is no statistically significant difference for the same biomarker between groups. Although previous studies have assessed thiol homeostasis in MS (47, 48), to the best of our knowledge, this is ...

Distinguished Chemical and Biological Engineering Professor Christopher Bowman’s research group has designed a novel thiol-thioester CANs which can be seamlessly incorporated into mature ...

151; -- Some alt-right and white supremacist groups are using the same online ... The most recent possible example is the Parkland, Florida, school rampage. After the deadly Feb.

The thiol groups are the primary targets of the reactive oxygen species. Thiol is an organic compound containing sulfhydryl (-SH) group which has a critical role in preventing the occurrence of ...

NSHD-1 and NSHD-2 are recently developed thiol-activated H2S donors designed for sustained release of H2S upon activation by molecules containing thiol groups such as cysteine and glutathione. We ...

Although in vivo models have limitations, they provide information not easily ascertained by in vitro studies. The identification of thiol isomerases as important components of thrombus formation is a ...