Thiamine (vitamin B1), riboflavin (vitamin B2) and niacin (vitamin B3) are essential nutrients involved in various physiological processes, playing a vital role in cellular energy metabolism.17 ...

Particularly, we noted that MetaCyc pathway “thiamine diphosphate salvage II” was significantly enriched in the obese group compared with the healthy controls . We also annotated the virulence genes ...

A research team led by Prof. Xiaoqiang Huang from Nanjing University has developed a novel non-natural dynamic kinetic ...

The crystal structure of the geranylgeranyl diphosphate synthase from Sinapis alba (mustard) has been solved in two crystal forms at 1.8 and 2.0 Å resolutions. In one of these forms, the dimeric ...

Isoprenyl diphosphate synthases (IDSs) catalyze condensation reactions of isoprene units to produce isoprenoids or terpenoids, the largest class of natural products on earth. IDSs are divided into ...

B vitamins are often praised for boosting energy, supporting brain function, and maintaining healthy skin and metabolism. But this essential group of water-soluble nutrients isn’t just one vitamin — ...

However, thiamine is also a vital micronutrient for plants; thiamine diphosphate (TDP) is well characterized in its role as an essential coenzyme to enzymes in central metabolism, including carbon ...

Creatine supplements demonstrated a hint of promise for people with Alzheimer's disease in the pilot CABA trial. In the single-arm study of 20 Alzheimer's patients who received 20 g/day of ...