Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, 199 Ren-Ai Road, Suzhou, Jiangsu 215123, China ...

However, these approaches struggle with alkyl halides due to the strength of the carbon–halogen bonds, says Fu, who led the work along with computational chemist Peng Liu, from the University of ...

The authors show that their reactions enable the deracemization of both tertiary alkyl halides (which contain quaternary carbon centres) and secondary alkyl halides (in which the carbon atom ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/jacs.5c02417. Experimental details: general information, preparation of ...

Medicinal chemists have been responsible for many of our modern medicines. Their central contribution to developing new therapeutic agents against microbial infections, cancer and heart disease has ...