In the ever-evolving field of longevity and anti-aging research, chemical sciences are making significant strides, ...

Cells from the telomerase knockout mouse immortalize with an approximately ten million-fold greater frequency than human cells. In this commentary, Wright and Shay discuss the implications of this ...

The targeting of telomeres offers promise for new cancer therapies, which can be aimed at disrupting the mechanisms that ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

Dorothy Shippen will soon retire, concluding a celebrated career marked by curiosity and a commitment to the next generation of scientists.

They found that the phenotype of the telomerase null offspring was similar to that of the late generation parent, although only half of the chromosomes were short. In addition, spectral karyotyping ...

The findings provide new insight into how human telomeres function at the molecular level, with implications for numerous diseases and disorders. "After the discovery of telomerase, it took ...

Genes and Bodily Functions Before discussing the key concepts related to aging and genetics ... It appears that while genes in all of our cells have the code word for the enzyme telomerase which ...

The initial steps in valve leaflet osteogenic reprogramming are not fully understood. As TERT (telomerase reverse transcriptase) overexpression primes mesenchymal stem cells to differentiate into ...

Today Early in the fall, experts might also see more cases of respiratory syncytial virus, Dr. Geeta Sood, assistant professor of medicine and epidemiologist at Johns Hopkins Bayview Medical Center, ...

Previous studies have indicated that magnesium maintains telomeric chromatin structure and integrity, as well as supports telomerase regulation. Genomic instability, which involves DNA damage ...