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Extremely long tail provides structural window into how bacteria-infecting viruses called phages assemble. A recent study in the Journal of Biological Chemistry has revealed the secret behind an ...
Hör said that Bil’s conjugation to the spike protein likely inhibits the interaction between the phage and its entry receptor on new host cells, which could explain why some of the tailed progenies ...
Phages, viruses that attack bacteria, have a head and a tail. The head contains the phage's genetic material and the tail is used to identify a potential host, that is, a bacterial cell into which ...
For clinical applications, researchers mostly use bacteriophages belonging to the order Caudovirales, also known as tailed phages. These phages contain receptor binding proteins in their tail fibers, ...
Phages are bundles of tangled ... Freeman was able to recreate the tail tube and, perhaps most tantalizingly, the tip of the tail, which binds to the bacteria. Currently, researchers do not ...
Over 90% of phages have tailed icosahedral heads that, after inserting their nucleic acid into the bacterial cell, terminate their infections by lysing the cells they have infected. Depending on ...
Today, he is a senior scientist at Pfizer. “Recent research,” he notes, “has primarily focused on tailed-phages and Microviridae. Phages can be lytic or exhibit other life cycles such as ...
The study, "A synthetic biology approach to assemble and reboot clinically relevant Pseudomonas aeruginosa tailed phages," was published in the journal Microbiology Spectrum. "Antimicrobial ...
The study, “A synthetic biology approach to assemble and reboot clinically relevant Pseudomonas aeruginosa tailed phages,” was supported by the Walder Foundation, the National Science ...
Unlike many of the viruses that infect humans and animals that contain only one compartment, phages consist of a tail attached to a spiky, prismlike protein shell that contains their DNA.
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