The results were clear: people with early Parkinson’s had higher levels of TSPO in their brains compared to people without ...

Multisystemic inflammation might be a key pathophysiologic mechanism in post–coronavirus disease 2019 (post-COVID) syndrome. N,N- diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)5,7dimethylpyrazolo[1,5a] ...

然而，现有神经炎症PET示踪剂如靶向TSPO（线粒体18 kDa转运蛋白）的放射性配体存在多态性敏感性问题，而MAO-B（单胺氧化酶B）配体仅能反映早期星形胶质细胞激活。更棘手的是，传统抗体因无法高效穿透血脑屏障（BBB）而难以用于脑部靶点成像。 针对这一技术 ...

Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI).