However, since TNF is a cytokine with pleiotropic effects, interfering with many immunological functions and pathways, the precise mechanisms by which these agents reduce inflammation in these ...

TNF Pharmaceuticals (TNFA), announced that it has initiated the first in a series of studies to evaluate the impact of its novel oral TNF-alpha ...

TNF-alpha inhibitors and interleukin inhibitors. Methotrexate slows down the growth rate of skin cells by binding to an enzyme that causes rapid skin cell growth and blocking its function.

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

TNF Pharmaceuticals (TNFA) announced that it has achieved a safety data milestone supporting expanded and longer-term clinical studies of its ...

The first study examines TNF-a levels in patients receiving the GLP-1 agonist Wegovy ® or Ozempic ® who show signs of increased inflammation associated with sarcopenia, which is the progressive loss ...

This function may be exploited for microRNA-mediated ... (A+U)-rich elements in the 3′ untranslated region (UTR) of the TNF alpha mRNA. Now the researchers introduce a miRNA as the mediator ...