Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to ...

This article explores the complex roles of cytokine networks in the development and progression of autoimmune diseases.

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008. Abstract and Introduction TNF Receptors ...

In order to test the hypothesis that tumor necrosis factor (TNF) signaling is involved in manifestation and progression of murine SAVI disease, we here used genetic inhibition of TNF receptors. TNF, a ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008. Abstract and Introduction TNF Receptors ...

TNF(tumor necrosis factor): Tumor necrosis factor is a substance in your body that causes inflammation. Learn about the role it plays in diseases like rheumatoid arthritis (RA).

Introduction. The TNF receptor superfamily (TNFRSF) comprises a diverse group of cell surface receptors involved in regulating immune responses, inflammation, and cell survival ().Dysregulation of TNF ...

Homozygous mice displayed a stem cell–intrinsic defect in hematopoiesis of all lineages due to excessive apoptosis induced by tumor necrosis factor (TNF)–dependent death signaling. Numerous transcript ...

Background— Tumor necrosis factor-α (TNF) is increased in myocardial tissue after ischemia and reperfusion (I/R). TNF contributes to postischemic myocardial dysfunction and induces proinflammatory ...