Transforming Growth Factor Beta (TGF‐β) signalling pathways are integral to a wide array of cellular processes, ranging from embryonic development to tissue homeostasis and immune regulation.

TGF-beta signaling also controls vascular development, with loss-of-function mutations in TGF-beta receptor 1 (TGFBR1/ALK5), TGFBR2, the EC accessory receptor Endoglin, or various SMADs producing ...

Endothelial cell-specific loss of TGF-beta signaling in mice leads to CNS vascular defects, specifically impairing retinal development and promoting immune cell infiltration. The data are solid, ...

A well-documented chemical modulator involved in various molecular signalling cascades, is transforming growth factor beta (TGF-ß). TGF-ß is a secreted cytokine that is present in three main isoforms ...

Follistatin-344 peptide has garnered significant attention in scientific research due to its intricate interactions with ...

Corbus Pharmaceuticals Holdings' financial position is stable for now, with about two years of cash runway. Click here to ...

Follistatin-344 (FS-344), a glycoprotein variant, has emerged as a focal point in scientific research due to its potential ...

Keros Therapeutics, Inc. (“Keros”) (Nasdaq: KROS), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapeutics to treat a wide range of patients with ...

Concludes Strategic Alternatives Review and Provides Update on Development of KER-065LEXINGTON, Mass., June 09, 2025 (GLOBE ...

AngII can activate the transforming growth factor-beta (TGF-β) signaling pathway, a crucial regulator of cell survival, brain homeostasis, angiogenesis, memory, and neuronal plasticity (Border and ...