This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Notably, RPE-1 cells with heterozygous deletion of the U-box domain show altered TGFB signaling responses, particularly in SMAD2 phosphorylation levels and AKT activation. Our findings suggest a novel ...

We evaluated the efficacy of heat shock protein 90 (Hsp90) inhibition as a novel approach to inhibition of aberrant transforming growth factor (TGF)-β signalling and for the treatment of fibrosis in ...

Correspondence to Professor Guy Boeckxstaens, Translational Research in Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (Chrometa), KU Leuven, Leuven, ...

Genetic alterations may help mosquitoes adjust to climate change, shifting the distribution of mosquito-borne disease in a warming planet.