T cell activation requires a T cell receptor (TCR) to recognize its cognate peptide in the context of an MHC molecule. In addition, the association of CD3 with the TCR–peptide–MHC complex ...

Medigene AG (Medigene, FSE: MDG1, Prime Standard), an oncology platform company focused on the research and development of T cell receptor ...

CD3具有五种肽链，即γ链、δ链、ε链、ζ链和η链，这五种链均为跨膜蛋白。CD3分子的跨膜区通过盐桥与TCR两条肽链的跨膜区连接，形成TCR-CD3复合体，共同参与T细胞对抗原的识别。TCR识别抗原所产生的活化信号由CD3转导至T细胞内。简而言之，CD3+T细胞是表面表达 ...

The structure of the endogenous or genetically engineered T-cell receptor (TCR)-CD3 complex can recognize peptides presented by HLA molecules originating from various cellular compartments. Created ...

The multi-target collaboration combines the respective expertise of each company with Medigene’s 3S (sensitive, specific and safe) TCR generation and characterization capabilities and EpimAb’s ...

The partnership leverages the sensitive, specific and safe (3S) TCR characterisation and generation capabilities of Medigene and EpimAb's cluster of differentiation 3 (CD3) antibody and TCR-Fab in ...

The multi-target collaboration combines the respective expertise of each company with Medigene’s 3S (sensitive, specific and safe) TCR generation and characterization capabilities and EpimAb’s ...