Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune ...

病例信息患者吕*，男，33岁，主因“发现血肌酐升高3月，周身水肿半月”入院。现病史：患者入院前3月因“原发性血小板减少症”复诊时发现血肌酐升高，为106μmol/L，当时无尿量及尿色改变，无下肢水肿，无恶心、呕吐，无胸闷憋、气，无脱发、光过敏，无皮疹 ...

最近的研究发现ECSIT在非免疫细胞和免疫细胞中对肿瘤发生有重要影响。肠道上皮细胞中ECSIT的缺失引起线粒体功能损伤并促进代谢重编程，谷氨酸代谢增加引起α-酮戊二酸/琥珀酸比率升高，进而促进TET去甲基化酶激活并诱导选择性翻译起始因子eIF4A1/ ...

Many cells in multicellular organisms are specialised. They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped ...