RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis patients.

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients ...

A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

A breakdown of how memory B, T, and innate cells remember past infections and how this insight powers vaccines and immunotherapies.

T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into ...

First gamma-delta (γδ) TCE to demonstrate significant γδ T cell expansion and activation, potentially offering an alternative to conventional CD3-based approaches without significant adverse events ...

γδT cells represent a unique and versatile subset of T cells characterized by the expression of T-cell receptors (TCRs) composed of γ and δ chains. Unlike conventional αβT cells, γδT cells do not ...

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies. T cell-based ...

It is not clear whether this conclusion applies to other T cell subsets. Here, we investigated the role of TCR characteristics in the fate choice of evolutionarily conserved innate-like T cells. We ...

Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases. As they work to shed light on ...

Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases. As they work to shed light on ...