RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis patients.

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients ...

A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

A breakdown of how memory B, T, and innate cells remember past infections and how this insight powers vaccines and immunotherapies.

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable ...

A multi-institutional study led by the Icahn School of Medicine at Mount Sinai reports one-third of patients with relapsed or ...

T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into ...

cMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

Our data suggest CD8 and CD4 T cells in the brain barrier regions of aged mice exhibit effector memory phenotype. In particular, Th2 cells, Tregs and distinct subsets of CD153+ T cells accumulated in ...

Combination treatment could also benefit patients with lung, bowel, pancreatic and other solid cancers who don’t respond to ...

Site-specific labeling revealed unique characteristics of inguinal and mesenteric T cells in the inflamed CNS, though these signatures were not clearly extrapolated to CD4+ subsets in MS CSF cells (46 ...