Here, we present a computational framework for unbiased combinatorial polyfunctionality analysis of antigen-specific T-cell subsets (COMPASS). COMPASS uses a Bayesian hierarchical framework to ...

5-Prime | T-Cell Subsets: On the Immunity Warpath How do T cells recognize their targets? The acquired immune system consists of two major cell types, T and B cells, which recognize specific antigens.

Scientists and clinicians at University College London (UCL) and Great Ormond Street Hospital (GOSH) have discovered a small subset of T-cells that may play a key role in whether chimeric antigen ...

"Our results showed that a subset of T cells, labeled as CD8-fit T cells, are capable of high motility and serial killing, found uniquely in patients with clinical response," reports first author ...

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable ...

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies. T cell-based ...

T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into ...

While they have no direct involvement in neutralizing foreign substances, CD4+ T cells have various functions that help produce a vigorous immune response. Though various subsets of them exist ...