Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

The three-signal model provides an empirical framework for innate instruction of adaptive immunity, but mainly discusses STAT-dependent cytokines in T cell activation and differentiation, while the ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

Research from the Voigt lab at the Babraham Institute has investigated the mechanism by which bivalency functions to poise ...

Altogether, developing T cells migration, differentiation, maturation, proliferation, and survival are tightly regulated by a variety of hormones produced both locally and in other endocrine glands, ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Scientist Sarallah Rezazadeh from the Icahn School of Medicine explores the molecular mechanisms behind adult stem cells as ...

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...