Next, we demonstrate that, in a single design cycle, it is possible to create functional, purely synthetic yeast promoters that achieve substantial expression levels (within the top sixth ...

题目：Design of synthetic promoters for cyanobacteria with generative deep-learning model 期刊：Nucleic Acids Research 影响因子：19.16 发表时间：2023.5.29 原文作者 ...

Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, announced a collaboration agreement with Astellas Pharma, a global life sciences company. Under the ...

In a paper now published in the journal Nature Communications, they describe three design principles for yeast ...

LONDON – Synthetic promoters – a new and controllable means of directing gene expression – are starting to be deployed to increase the potency and specificity of gene therapies and to boost yields in ...

ESO-T01 is the first in vivo B-cell maturation antigen (BCMA) CAR-T candidate to reach the clinical stage and utilises a synthetic promoter designed using Chromatin Bio’s proprietary promoter design ...

ESO-T01 is the first in vivo B-cell maturation antigen (BCMA) CAR-T candidate to reach the clinical stage and utilises a synthetic promoter designed using Chromatin Bio's proprietary promoter ...

The molecules produced include important therapeutic proteins that can be expressed in a plant by altering its synthetic switches or metabolic pathways. Genetic elements like DNA promoters and ...

Using a transient expression system, the researchers demonstrated that the synthetic transcription factors and their target DNA sequences (promoters) are able to direct specific and tunable ...

What we focus on is containment – ensuring the bacteria is only active within the tumor. We achieve this by engineering a biosensor library in the lab. We design synthetic promoters that respond to ...