The study highlights the crucial role of succinyl-CoA in tumor immunity by inducing the succinylation of PD-L1. We identified the succinyltransferase CPT1A as a potential therapeutic target.

3D cellular-specific epigenetic and transcriptomic reprogramming is critical to organogenesis and tumorigenesis. Here, we dissect the distinct cell fitness in 2D (normoxia vs. chronic hypoxia) vs 3D ...

Department of Applied Chemistry and Chemical Engineering, University of Dhaka, Dhaka 1000, Bangladesh Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, ...

This study presents a valuable finding and developed ME3BP-7 as a novel microencapsulated formulation of 3BP, which specifically targets MCT1-overexpressing PDAC cells. It demonstrates its specificity ...

7 followers Cambridge, UK https://proteomics.bio.cam.ac.uk/research-themes ...

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