"This inhibition raises the levels of 7-dehydrocholesterol (7-DHC), suppresses cholesterol synthesis, and generates a sterol profile indistinguishable from that seen in congenital metabolic ...

The Editorial "Medication-induced sterol disruption: An overlooked threat to brain development and public health" appears ...

An editorial published in Brain Medicine reveals that many widely prescribed medications may disrupt sterol biosynthesis—an ...

Both high-cholesterol diets given to ameliorate cholesterol deficiency while decreasing 7-DHC and cholesterol-enriched diets plus simvastatin to further decrease sterol synthesis have been used as ...

"This inhibition raises the levels of 7-dehydrocholesterol (7-DHC), suppresses cholesterol synthesis, and generates a sterol profile indistinguishable from that seen in congenital metabolic ...

Using a synthetic antibody fragment, we found a sterol molecule that is critical for activation of the Smoothened receptor in Hedgehog pathway signaling. https://lnkd.in/grGs8ih ...

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