Short chain fatty acylations establish connections between cell metabolism and regulatory pathways. Lysine acetoacetylation (Kacac) was recently identified as a new histone mark. However, regulatory ...

Traditional Chinese medicine offers promising natural compounds that modulate cholesterol metabolism, unveiling new therapeutic pathways for cancer treatment. Study: Targeting cholesterol ...

MPST upregulates the sterol regulatory element-binding protein 1c pathway, C-Jun N-terminal kinase phosphorylation and hepatic oxidative stress, which is mediated by inhibition of CSE/H 2 S. How might ...

Among them, acetyl-CoA also participates in lipid synthesis in the organism, generating long chain fatty acid (LCFA, the process is also known as de novo lipogenesis) under the promotion of ...

Led by Ryan Flynn, MD, PhD, assistant professor of stem cell and regenerative biology at Harvard Medical School (HMS), the study identified one RNA-binding protein on the cell surface, NPM1 ...

The subsequent translocation of CAR protein into the nucleus is accompanied by dimerization with the RXRα and binding to regulatory DNA elements of target genes. Activated CAR then alters the ...

This study investigates the effects of nobiletin, a citrus flavonoid, on high-fat-diet-induced obesity-related muscle atrophy and its regulatory role in bile acid metabolism ... Furthermore, nobiletin ...

Among these proteins were several calcium-binding proteins, such as calpain-2, whose gene has recently been identified to retain a memory trace even after a training break. "At the level of the ...

Search for other works by this author on: ...