Sterols, such as cholesterol ... act allows for the formation of membrane domains—self-assembling structures that are believed to organize proteins in cell membranes. The work tests and revises ...

The first step of successful infection by any intracellular pathogen relies on its ability to invade its host cell membrane. However, the detailed structural and molecular ... KMP-11 can form ...

C-4 methylated sterols are synthesized in the cytosol and localized to the outer membrane, suggesting that a bacterial sterol transport machinery ... including in some pathogens that use host sterol ...

Using fluorescent analogs of cholesterol and quantitative fluorescence microscopy, we have recently measured the transport kinetics of sterol between plasma membrane (PM), recycling endosomes (REs) ...

Nutrient starvation initiates cell cycle exit and entry into quiescence ... and was accompanied by a shift of the cellular lipid profile from membrane towards storage lipids, driven by a ...

Cell polarity is essential for generating diverse cell functions. The underlying mechanisms of how a cell establishes, maintains, and changes its polarity are poorly understood. Recently, sterol-rich ...

† Department of Pharmaceutical Technology and Biochemistry and ‡ Department of Physical Chemistry, Gdansk University of Technology, Gdansk, Poland § Department of Pharmaceutical Chemistry, Medical ...