Overall, the ongoing research into peptidoglycan biosynthesis inhibitors, particularly those targeting MurA, reflects a concerted effort to address the challenges posed by antibiotic resistance.

Some commonly prescribed drugs, such as trazodone and aripiprazole, have been found to inhibit sterol biosynthesis, leading to increased levels of 7-DHC and decreased cholesterol levels in the brain.

Two enzyme inhibitors join forces in reducing bladder cancer cell proliferation. n 1996, molecular biologist Kun Ping Lu, a ...

DURECT Corporation (Nasdaq: DRRX) today announced the publication of a peer-reviewed article on the AHFIRM trial data in NEJM ...

Graca et al. reports a fundamental missing link in the ethanol metabolism of mycobacteria and illuminates the role of a flavoprotein dehydrogenase that acts as an electron shuttle between an uncommon ...

Biochemistry Unit, Institute of Child Health and Metabolic Unit, Great Ormond Street Hospital for Children, London Dr Peter T Clayton, Biochemistry Unit, Institute of Child Health, 30 Guilford Street, ...

Helmholtz Institute for Pharmaceutical Research (HIPS)−Helmholtz Centre for Infection Research (HZI), Saar-land University, Campus E8.1, 66123Saarbrücken, Germany Department of Pharmacy, Saarland ...

The intricate link between cholesterol metabolism and host immune responses is well recognized, but the specific mechanisms by which cholesterol biosynthesis influences hepatitis B virus (HBV) ...

This valuable work examines the role of the oxidoreductase MftG in Mycolicibacerium smegmatis alcohol metabolism. A solid set of data is presented to show that, in the context of ethanol metabolism, ...

Cardiovasc Rev Rep. 2004;25(5) © 2004 Le Jacq Communications, Inc. Cite this: Inhibition of Cholesterol Absorption by Ezetimibe -- A New Approach in Lowering ...

Ezetimibe the first approved direct inhibitor of intestinal cholesterol absorption inhibits the absorption of dietary and biliary cholesterol without affecting absorption of triglycerides and ...