8. However, our findings clarified a new S1P-mediated signaling pathway, different from the one mediated by LPA. We found that S1P-induced VEGF-C expression was dependent on the MMP-2, FGF-1 ...

Sphingosine-1-phosphate (S1P ... In addition, inhibition of S1PR2 results in decreased matrix metalloproteinase (MMP)-9 activity in vivo and lower gelatinase activity in cerebral microvessels.

February 13, 2007 (San Francisco) — A bedside test for matrix metalloproteinase 8 (MMP-8) may help identify which patients with preterm premature rupture of membranes (PROM) have intra-amniotic ...