We validated several tumor-specific antigens using targeted mass spectrometry, peptide-HLA refolding and ribosome profiling. For example, we demonstrate that antigens derived from alternatively ...

However, its application to solid tumors remains constrained by antigen heterogeneity and on-target, off-tumor toxicities. One critical emerging approach to combat this challenge is logic-gated ...

Metastatic castration-resistant prostate cancer causes urinary symptoms, fatigue, pain, and more. This article covers the ...

Antibody-drug conjugates combined with immunotherapy have redefined the standard of care for advanced bladder cancer, ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

AI is enabling the development of a next generation of drugs that can more precisely target cancer cells while sparing ...

Metastatic castration-resistant prostate is an advanced form of the cancer that’s incurable. Learn about treatment options ...

These include producing the fluid that nourishes and transports sperm, secreting prostate-specific antigen (PSA), a ... a diagnosis of prostate cancer at some point in their life.

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.