The findings suggest that somatic growth deceleration primarily results not from an increase in cell-cycle time but from a decrease in growth fraction (fraction of cells that continue to proliferate).

Figure 4: DSBs accumulate predominantly in the late S/G 2 phase of the cell cycle. Transgenic mice were created by injection of the MT construct into C57BL/6 oocytes. Four founder lines were ...

and found that somatic cells have almost no activation of telomerase during three phase of cell cycle. The level of TERT mRNA and active telomerase in most phases of cell cycle (G0/G1, G1/S ...

The cell cycle relies on ubiquitin and the SCF complex plays an integral role in the regulation of this process. Ubiquitin ligase also regulates ubiquitinylation by stimulating the degradation of ...