Somatic cell cycle consists of four phases while early embryonic cell cycle alternates between S and M phases without intervening G1 and G2 phases. Different models of cell cycle regulation ...

The findings suggest that somatic growth deceleration primarily results not from an increase in cell-cycle time but from a decrease in growth fraction (fraction of cells that continue to proliferate).

and found that somatic cells have almost no activation of telomerase during three phase of cell cycle. The level of TERT mRNA and active telomerase in most phases of cell cycle (G0/G1, G1/S ...

Cell cycle speed is key to making aging cells young again Date: January 30, 2014 Source: Yale University Summary: Researchers identified a major obstacle to converting cells back to their youthful ...

To recapitulate the entire female germline life cycle with stem cells ... 1 Starting with mouse embryonic stem cells, these investigators generated fetal ovarian somatic cells, which supported ...

Company to showcase preclinical studies of ARV-393, an investigational oral PROTAC BCL6 degrader, as a single agent in models ...

Somatic mutations are considered to be the origin of cancer, the major disease of older adults, and they produce the cancer-cell phenotype. Here, we review a less familiar, less explored aspect of ...