Myosin Light Chain Kinase Substrate (Smooth Muscle) 介绍. 一、基本信息. 英文名称：Myosin Light Chain Kinase Substrate (Smooth Muscle); 中文名称：平滑肌肌球蛋白轻链激酶底物（暂未有更简洁通用的中文译名）; 氨基酸序列：赖氨酸 - 赖氨酸 - 精氨酸 - 丙氨酸 - 丙氨酸 - 精氨酸 - ...

Abstract—We investigated expression of the 5′-spliced isoform of smooth muscle myosin heavy chain (SM-MHC-B) in smooth muscle cells of cardiac vessels of the left ventricle of normotensive ...

Blebbistatin is a potent and specific inhibitor of the motor functions of class II myosins, including striated muscle myosin and nonmuscle myosin-2 (NM2). However, the blebbistatin inhibition of NM2c ...

Introduction. In vascular smooth muscle (VSM), contraction is initiated by phosphorylation of the regulatory light chain (RLC 20) of SM myosin II on Ser19 by the SM myosin light chain kinase (smMLCK, ...

Dynamic regulation of myosin filaments is a crucial factor in the ability of airway smooth muscle (ASM) to adapt to a wide length range. Increased stability or robustness of myosin filaments may play ...

After decades of debate over the structure of smooth muscle myosin filaments, it is still unclear whether they are helical, as in all other muscle types, or square in shape. In both cases bipolar ...

Introduction. Smooth muscle (SM) cells line the walls of hollow organs, including the gastrointestinal tract, vasculature, uterus and bladder, and they maintain homeostasis and responses to imposed ...

Abstract In the aortic wall of mammalian species, the maturation phase of smooth muscle cell (SMC) lineage is characterized by two temporally correlated but opposite regulatory processes of gene ...

Smooth muscle myosin light chain kinase (smMLCK) is a member of a diverse group of serine/threonine kinases that feature cytoskeletal association. Its catalytic activity is triggered by a ...

The smooth muscle myosin kinase (smMLCK) is a catalytically active serine/therosine kinase which is triggered by a conformational change upon Ca 2+ /calmodulin (Ca 2+ /CaM) binding. smMLCK shows a ...

SOUTH SAN FRANCISCO, Calif., Nov. 07, 2016 (GLOBE NEWSWIRE) -- Cytokinetics, Inc. (Nasdaq:CYTK) a leader in muscle biology and the mechanics of muscle performance, today announced the publication of ...