Myosin II molecules assemble and form filaments through their C-terminal rod region, and the dynamic filament assembly−disassembly process of nonmuscle myosin II molecules is important for cellular ...

A better understanding of smooth muscle development and differentiation will help us more clearly define the vascular disease process. Smooth muscle cells (SMCs) in the large vessels close to the ...

Enlargement, Reduction, and Even Reversal of Relative Migration Speeds of Endothelial and Smooth Muscle Cells on Biomaterials Simply by Adjusting RGD Nanospacing. Junhao He. Junhao He. State Key ...

Vascular SMC differentiation in embryonic development is recognized by the appearance of cytoskeletal and contractile protein isoforms, including SMα-actin (Acta2), SM-calponin (Cnn1), and SM-myosin ...

MT-125 is a selective inhibitor of non-muscle myosin II (NMII), a molecular motor protein that drives tumor proliferation and invasion, resistance to therapy and oxidative stress, and immune evasion.