Slides were imaged using SP8 fluorescence confocal microscope (Leica) and apochromatic glycerol immersion objectives ... Labelled cells were trypsyized and plated in a 1:1 ratio (PAAF:PASMC) in a ...

Molecular docking revealed that Digoxin could bind to DVL1 and reduce oxidative stress in SIC. The DVL1 gene module related to SIC was identified by means of WGCNA, and the immune infiltration ...

Abstract The effect of cyclosporin A on induction of nitric oxide synthase in rat aortic smooth muscle cells was examined. A combination of interleukin-1α (100 U/mL) and tumor necrosis factor−α (5000 ...

Muscle cells, for example, use tons of energy, causing their mitochondria to release lots of a side product of energy processing: reactive oxygen species such as hydrogen peroxide. These ...

Department of Endocrinology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life ...

Hence, scientists took this opportunity to explore the subtle processes occurring in living organisms. Nevertheless, such observations are complex─they require delicate samples kept in the liquid ...

Following an injury, regulatory T cells flock to damaged muscle. Their numbers peak four days later, after which the tissue goes from an inflammatory state to an anti-inflammatory state. It’s thought ...

The pathogenesis of atherosclerosis is complex, evolves, and involves many cell types. Macrophages and vascular smooth muscle cells (VSMCs ... Coverslips were counterstained with DAPI and mounted on ...