The children also failed to meet the criteria for a rare genetic condition called Smith-Lemli-Opitz, which hampers brain development in fetuses by disrupting cholesterol production in fetuses.

The Smith-Lemli-Opitz syndrome (SLOS) is the first-described in a growing family of hereditary defects in cholesterol biosynthesis, and presents with a spectrum of serious abnormalities ...

Deficient cholesterol and/or excessive 7-dehydrocholesterol (7-DHC) may be responsible for the pathology of Smith-Lemli-Opitz syndrome (SLOS). Both high-cholesterol diets given to ameliorate ...

The birth defects in the babies closely resemble a rare genetic condition called Smith-Lemli-Opitz. It’s a condition that affects how fetuses make cholesterol, which is critical for the brain to ...

Smith-Lemli-Opitz syndrome (SLOS) is a prototypical disorder arising from mutations in the gene encoding 7-dehydrocholesterol reductase (DHCR7). The resultant enzymatic deficiency leads to an ...

The birth defects in the babies closely resemble a rare genetic condition called Smith-Lemli-Opitz. It’s a condition that affects how fetuses make cholesterol, which is critical for the brain to ...

A single prescription could potentially tip their biochemical balance, with two or more medications sending them into a state resembling Smith-Lemli-Opitz Syndrome, a serious developmental disorder.