In the presence of (−)-sparteine or a (+)-sparteine surrogate, organolithiums add to N-alkenyl-N′-arylureas to give benzylic organolithiums in an enantioselective manner. Under the influence of DMPU, ...

Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained from 2345 acute leukemia ...