Although statins lower LDL-C, emerging evidence suggests that they may counteract the beneficial adaptations to exercise in skeletal muscle mitochondria and whole-body aerobic capacity. The underlying ...

A new technique that alters protein production in mitochondria could help researchers understand mitochondrial diseases as ...

Knockout of Foxk2 in MuSCs results in skeletal muscle dysplasia in mice and disrupts mitochondrial homeostasis in MuSCs. CoQ10 exhibits a therapeutic effect in the mouse model. FOXK2 deficiency ...

Mitochondria supply the body with the energy currency adenosine triphosphate (ATP), which drives all bodily activities. For ...

The presence of z disc streaming, focal deletions of myofibrils, atrophic muscle fibres, enlarged mitochondria (mitochondria extend over the length of two sarcomeres), subsarcolemmal mitochondria, and ...

We focus on looks and performance, but muscle’s metabolic, anti-inflammatory, and disease-resisting properties make it an ...

Expression of the uncoupling protein Ucp in skeletal muscle prevents ... are replete with mitochondria. These mitochondria are different from those in muscle or liver. In muscle, β-oxidation ...

Defects in this process lead to serious and often fatal disorders that can affect skeletal muscle and nerve cells as well as the heart. The results have been published in the renowned journal “Science ...

This month's cover highlights the article EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer by Dana Krauß, Maria Sibilia and colleagues. The tumor-intrinsic role of ...

1 The Second People's Hospital of Yuhuan, Yuhuan, China 2 Department of Nursing, College of Medical Science, Huzhou University, Huzhou, China Objective: To explore the relationship between skeletal ...

Skeletal muscle stores 95% of the body's creatine, with the liver, kidneys, and brain storing the remaining 5%.