Strand information was lost ... It will be interesting to see how the UMI approach could improve single-cell RNA sequencing. Furthermore, the capture efficiency of conversion of mRNA into ...

Using capillary gel electrophoresis, researchers from the National Institute of Health Sciences in Kanagawa, Japan studied the factors that optimize chain-length distribution analysis of messenger RNA ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

A closing session on Day 1 of HPLC on Monday, June 15, 2025, ended with a topic that is on everyone’s lips in separation science: oligonucleotide analysis. The session was chaired by two luminaries in ...

2. Elongation commences when RNA polymerase unwinds double-stranded DNA into two single strands. These DNA strands are used as genetic templates for RNA synthesis. As the DNA template strand moves ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one ...

Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...

It is tiny: If you stacked molecules of RNA side by side, you could fit 50,000 of them within the breadth of a single human hair. What it lacks in size it makes up for in versatility. Because it is a ...

RNA only has one strand, but like DNA, is made up of nucleotides. RNA strands are shorter than DNA strands. RNA sometimes forms a secondary double helix structure, but only intermittently. DNA is a ...

In a recent study posted to the bioRxiv* preprint server, researchers performed single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic profiling of livers from deceased coronavirus ...

RNA is similar to DNA but is usually a single strand of “letters,” or base pairs, rather than a double strand, and it typically conveys messages from DNA that instruct the body to make proteins.