Scientists see the first steps of DNA unwinding
For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...
Game Rant14 小时
Pokemon Fan Crochets Chimchar and Its Evolutions
A Pokemon fan artist crafts Chimchar, Monferno, and Infernape as crochet dolls and shares their handiwork with their fellow ...
News-Medical.Net on MSN17 小时
Breakthrough study unveils mechanics of DNA unwinding
For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...
生物通3 小时
结构动力学新解：复制解旋酶如何解开 DNA 双链
研究结论与讨论部分指出，LTag 通过一种由 ATP 结合和水解调节的反式别构、熵驱动机制在单链 DNA 上进行转位。这种机制可能广泛适用于使用旋转循环的六聚体解旋酶，为理解其他类似解旋酶的工作原理提供了重要参考。同时，研究人员还提出了双向叉解开的模型，解释了 LTag 如何在复制起始位点驱动 DNA 解链和双向复制叉的建立。这一模型不仅适用于 SV40 系统，在真核生物系统中也可能具有相似的机制 ...