Meal memories stored in the hippocampus help control hunger timing. Disrupting these memories in rats led to more frequent ...

Scientists at the University of California, Davis have developed a new drug related to LSD that retains the psychedelic’s ...

Here, we investigated the neuropharmacology of 5-MeO-DMT and several of its N-alkyl, N-allyl, and 2-methyl analogs, with three major aims: 1) to determine in vitro receptor profiles for the compounds, ...

Here, we investigated the neuropharmacology of 5-MeO-DMT and several of its N-alkyl, N-allyl, and 2-methyl analogs, with three major aims: 1) to determine in vitro receptor profiles for the compounds, ...

Edited by Solomon H. Snyder, The Johns Hopkins University School of Medicine, Baltimore, MD, and approved January 29, 2016 (received for review December 28, 2015) The PFC is densely innervated by ...

Image of a cortical neuron (white) expressing serotonin 2A (5-HT2A) receptors (multicolor). New work shows that engaging 5-HT2A receptors inside cells, but not on the cell surface, encourages cell ...

Sleep deprivation increases the levels of serotonin 2A neurotransmitter receptors within 6 - 8 hours. Abnormal serotonin 2A receptor function is associated with hallucinations, cognitive impairment, ...

Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. Molecular Psychiatry, 2022; DOI: 10.1038/s41380-021-01390-w; ...

Abstract. Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. Serotonin 2A receptors (5-HT 2A Rs) mediate the hallucinogenic ...

The serotonin 2A (5-HT 2A) receptor is widely distributed in the brain and plays a critical role in perception, cognition and psychosis. It is also responsible for the psychedelic effects of drugs ...

Meal choice elicits a rapid metabolic reprogramming that indicates a potentiation of TCA cycle and amino acid metabolism, which requires serotonin 2A receptor. Knockdown of glutamate dehydrogenase, a ...