Mutations in sarcomere protein genes account for approximately ... Elucidation of the components of these pathways may suggest therapeutic interventions that are also relevant to hypertrophic ...

The sarcomere is subdivided in several regions ... you need to picture its components in their natural environment -- one of the biggest challenges in biological research nowadays that cannot ...

Scientists have produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, using electron cryo-tomography (cryo-ET). The ...